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Induction of protective CD4+ T cell-mediated immunity by a Leishmania peptide delivered in recombinant influenza viruses.
The available evidence suggests that protective immunity to Leishmania is achieved by priming the CD4(+) Th1 response. Therefore, we utilised a reverse genetics strategy to generate influenza A viruses to deliver an immunogenic Leishmania peptide. The single, immunodominant Leishmania-specific LACK(...
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| Pubblicato in: | PLoS ONE |
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| Autori principali: | , , , , , , |
| Natura: | Articolo |
| Pubblicazione: |
Public Library of Science (PLoS)
2012-01-01
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| Accesso online: | https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22470440/?tool=EBI |
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