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The flavoheme reductase Ncb5or protects cells against endoplasmic reticulum stress-induced lipotoxicity[S]
NCB5OR is a novel flavoheme reductase with a cytochrome b5-like domain at the N-terminus and a cytochrome b5 reductase-like domain at the C terminus. Ncb5or knock-out mice develop insulin deficient diabetes and loss of white adipose tissue. Ncb5or−/− mice have impairment of Δ9 fatty acid desaturatio...
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| Publicado no: | Journal of Lipid Research |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Publicado em: |
Elsevier
2010-01-01
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| Assuntos: | |
| Acesso em linha: | http://www.sciencedirect.com/science/article/pii/S0022227520313754 |
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