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A Simple and Robust Single-Step Method for CAR-Vδ1 γδT Cell Expansion and Transduction for Cancer Immunotherapy

The γδT cell subset of peripheral lymphocytes exhibits potent cancer antigen recognition independent of classical peptide MHC complexes, making it an attractive candidate for allogeneic cancer adoptive immunotherapy. The Vδ1-T cell receptor (TCR)-expressing subset of peripheral γδT cells has remaine...

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Detalhes bibliográficos
Publicado no:Frontiers in Immunology
Main Authors: Gabrielle M. Ferry, Charles Agbuduwe, Megan Forrester, Sophie Dunlop, Kerry Chester, Jonathan Fisher, John Anderson, Marta Barisa
Formato: Artigo
Publicado em: Frontiers Media S.A. 2022-05-01
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Acesso em linha:https://www.frontiersin.org/articles/10.3389/fimmu.2022.863155/full
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