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Proglucagon-Derived Peptides Expression and Secretion in Rat Insulinoma INS-1 Cells

Rat insulinoma INS-1 cells are widely used to study insulin secretory mechanisms. Studies have shown that a population of INS-1 cells are bi-hormonal, co-expressing insulin, and proglucagon proteins. They coined this population as immature cells since they co-secrete proglucagon-derived peptides fro...

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Detalhes bibliográficos
Publicado no:Frontiers in Cell and Developmental Biology
Main Authors: Ana Acosta-Montalvo, Chiara Saponaro, Julie Kerr-Conte, Jochen H. M. Prehn, François Pattou, Caroline Bonner
Formato: Artigo
Publicado em: Frontiers Media S.A. 2020-11-01
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Acesso em linha:https://www.frontiersin.org/articles/10.3389/fcell.2020.590763/full
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