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Circulating tumor DNA: Opportunities and challenges for pharmacometric approaches

To support further development of model-informed drug development approaches leveraging circulating tumor DNA (ctDNA), we performed an exploratory analysis of the relationships between treatment-induced changes to ctDNA levels, clinical response and tumor size dynamics in patients with cancer treate...

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Detalhes bibliográficos
Publicado no:Frontiers in Pharmacology
Main Authors: Benjamin Ribba, Andreas Roller, Hans-Joachim Helms, Martin Stern, Conrad Bleul
Formato: Artigo
Publicado em: Frontiers Media S.A. 2023-03-01
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Acesso em linha:https://www.frontiersin.org/articles/10.3389/fphar.2022.1058220/full
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