Gastrula‐Premarked Posterior Enhancer Primes Posterior Tissue Development Through Cross‐Talk with TGF‐β Signaling Pathway

Abstract The regulatory mechanisms governing cell fate determination, particularly lineage diversification during mammalian embryonic development, remain poorly understood with in‐depth regulatory paradigms yet to be fully elucidated. Here, leveraging the epigenetic landscape of mouse gastrula, p‐En...

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Publicado no:Advanced Science
Main Authors: Yingying Chen, Fengxiang Tan, Qing Fang, Lin Zhang, Jiaoyang Liao, Penglei Shen, Yun Qian, Mingzhu Wen, Rui Song, Yonggao Fu, He Jax Xu, Ran Wang, Cheng Li, Zhen Shao, Jinsong Li, Naihe Jing, Xianfa Yang
Formato: Artigo
Publicado em: Wiley 2025-09-01
Assuntos:
Enhancer RNA
Posterior tissue development
Pre‐marked enhancer
TGF‐β signaling
Acesso em linha:https://doi.org/10.1002/advs.202500895
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https://doi.org/10.1002/advs.202500895

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