Comparison of Mesenchymal Stromal Cells From Different Origins for the Treatment of Graft-vs.-Host-Disease in a Humanized Mouse Model

Mesenchymal stromal cells (MSCs) have potent immunomodulatory properties that make them an attractive tool against graft- vs.-host disease (GVHD). However, despite promising results in phase I/II studies, bone marrow (BM-) derived MSCs failed to demonstrate their superiority over placebo in the sole...

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Detalhes bibliográficos
Publicado no:Frontiers in Immunology
Main Authors: Céline Grégoire, Caroline Ritacco, Muriel Hannon, Laurence Seidel, Loïc Delens, Ludovic Belle, Sophie Dubois, Sophie Vériter, Chantal Lechanteur, Alexandra Briquet, Sophie Servais, Gregory Ehx, Yves Beguin, Frédéric Baron
Formato: Artigo
Publicado em: Frontiers Media S.A. 2019-04-01
Assuntos:
Mesenchymal stromal cells
Graft-vs.-host-disease
Hematopoietic stem cell transplantation
Xenogeneic
NSG
Bone marrow
Acesso em linha:https://www.frontiersin.org/article/10.3389/fimmu.2019.00619/full
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https://www.frontiersin.org/article/10.3389/fimmu.2019.00619/full

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