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Cross-talk between Hippo and Wnt signalling pathways in intestinal crypts: Insights from an agent-based model

Intestinal crypts are responsible for the total cell renewal of the lining of the intestines; this turnover is governed by the interplay between signalling pathways and the cell cycle. The role of Wnt signalling in cell proliferation and differentiation in the intestinal crypt has been extensively s...

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Detalhes bibliográficos
Publicado no:Computational and Structural Biotechnology Journal
Main Authors: Daniel Ward, Sandra Montes Olivas, Alexander Fletcher, Martin Homer, Lucia Marucci
Formato: Artigo
Publicado em: Elsevier 2020-01-01
Assuntos:
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2001037019301217
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