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Cell fate decisions of human iPSC-derived bipotential hepatoblasts depend on cell density.
During embryonic development bipotential hepatoblasts differentiate into hepatocytes and cholangiocytes- the two main cell types within the liver. Cell fate decision depends on elaborate interactions between distinct signalling pathways, namely Notch, WNT, TGFβ, and Hedgehog. Several in vitro protoc...
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| Publicado no: | PLoS ONE |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Publicado em: |
Public Library of Science (PLoS)
2018-01-01
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| Acesso em linha: | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0200416&type=printable |
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