The hemagglutinin proteins of clades 1 and 2.3.4.4b H5N1 highly pathogenic avian influenza viruses exhibit comparable attachment patterns to avian and mammalian tissues

ABSTRACT The global spread of the A/goose/Guangdong/1/96-lineage H5N1 highly pathogenic avian influenza (HPAI) viruses has been accompanied by an expanded host range and the establishment of sustained viral transmission among dairy cattle. To evaluate if the evolving H5N1 viruses have changed tissue...

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Publicado en:Journal of Virology
Autores principales: Bingkuan Zhu, Kevin Fung, Hailey Huiyi Feng, Julia A. Beatty, Fraser Hill, Anne C. N. Tse, Christopher J. Brackman, Thomas H. C. Sit, Agnès Poujade, Nicolas Gaide, Mariette Ducatez, Gilles Foucras, Malik Peiris, Shih-Chieh Ti, John M. Nicholls, Hui-Ling Yen
Formato: Artículo
Publicado: American Society for Microbiology 2025-10-01
Materias:
Highly pathogenic avian influenza (HPAI)
Clade 2.3.4.4b
Recombinant HA protein
Tissue tropism
Acceso en línea:https://journals.asm.org/doi/10.1128/jvi.00976-25
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https://journals.asm.org/doi/10.1128/jvi.00976-25

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