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Characterization of Human CD4 T Cells Specific for a C-Peptide/C-Peptide Hybrid Insulin Peptide
Hybrid Insulin Peptides (HIPs), which consist of insulin fragments fused to other peptides from β-cell secretory granule proteins, are CD4 T cell autoantigens in type 1 diabetes (T1D). We have studied HIPs and HIP-reactive CD4 T cells extensively in the context of the non-obese diabetic (NOD) mouse...
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| Publicado no: | Frontiers in Immunology |
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| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Publicado em: |
Frontiers Media S.A.
2021-05-01
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| Assuntos: | |
| Acesso em linha: | https://www.frontiersin.org/articles/10.3389/fimmu.2021.668680/full |
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