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Acquired Drug Resistance Enhances Imidazoquinoline Efflux by P-Glycoprotein
Multidrug-Resistant (MDR) cancers attenuate chemotherapeutic efficacy through drug efflux, a process that transports drugs from within a cell to the extracellular space via ABC (ATP-Binding Cassette) transporters, including P-glycoprotein 1 (P-gp or ABCB1/MDR1). Conversely, Toll-Like Receptor (TLR)...
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| Publicado no: | Pharmaceuticals |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Publicado em: |
MDPI AG
2021-12-01
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| Assuntos: | |
| Acesso em linha: | https://www.mdpi.com/1424-8247/14/12/1292 |
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