Increasing human monoclonal antibody cloning efficiency with a whole-cell modified immunoglobulin-capture assay (mICA)

Expression cloning of fully human monoclonal antibodies (hmAbs) is seeing powerful utility in the field of vaccinology, especially for elucidating vaccine-induced B-cell responses and novel vaccine candidate antigen discovery. Precision of the hmAb cloning process relies on efficient isolation of hm...

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Bibliografiset tiedot
Julkaisussa:Frontiers in Immunology
Päätekijät: Sara Siris, Camilla A. Gladstone, Yanping Guo, Radhika Patel, Christopher L. Pinder, Robin J. Shattock, Paul F. McKay, Paul R. Langford, Fadil A. Bidmos
Aineistotyyppi: Artikkeli
Julkaistu: Frontiers Media S.A. 2023-06-01
Aiheet:
Neisseria meningitidis
Streptococcus pneumoniae
Reverse vaccinology 2.0
Human monoclonal antibodies
Vaccines
Plasmablast enrichment
Linkit:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1184510/full
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https://www.frontiersin.org/articles/10.3389/fimmu.2023.1184510/full

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