Inferred Allelic Variants of Immunoglobulin Receptor Genes: A System for Their Evaluation, Documentation, and Naming

Immunoglobulins or antibodies are the main effector molecules of the B-cell lineage and are encoded by hundreds of variable (V), diversity (D), and joining (J) germline genes, which recombine to generate enormous IG diversity. Recently, high-throughput adaptive immune receptor repertoire sequencing...

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Publicado no:Frontiers in Immunology
Main Authors: Mats Ohlin, Cathrine Scheepers, Martin Corcoran, William D. Lees, Christian E. Busse, Davide Bagnara, Linnea Thörnqvist, Jean-Philippe Bürckert, Katherine J. L. Jackson, Duncan Ralph, Chaim A. Schramm, Nishanth Marthandan, Felix Breden, Jamie Scott, Frederick A. Matsen IV, Victor Greiff, Gur Yaari, Steven H. Kleinstein, Scott Christley, Jacob S. Sherkow, Sofia Kossida, Marie-Paule Lefranc, Menno C. van Zelm, Corey T. Watson, Andrew M. Collins
Formato: Artigo
Publicado em: Frontiers Media S.A. 2019-03-01
Assuntos:
Immunoglobulin
Allelic variation
Inference
AIRR-seq
IGHV
V(D)J rearrangement
Acesso em linha:https://www.frontiersin.org/article/10.3389/fimmu.2019.00435/full
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https://www.frontiersin.org/article/10.3389/fimmu.2019.00435/full

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