Alternagin-C, a disintegrin-like protein from the venom of Bothrops alternatus, modulates alpha2ß1 integrin-mediated cell adhesion, migration and proliferation

The alpha2ß1 integrin is a major collagen receptor that plays an essential role in the adhesion of normal and tumor cells to the extracellular matrix. Alternagin-C (ALT-C), a disintegrin-like protein purified from the venom of the Brazilian snake Bothrops alternatus, competitively interacts with the...

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發表在:Brazilian Journal of Medical and Biological Research Brazilian Journal of Medical and Biological Research, Volume: 38, Issue: 10, Pages: 1505-1511, Published: OCT 2005
Main Authors: Selistre-de-Araujo, H.S., Cominetti, M.R., Terruggi, C.H.B., Mariano-Oliveira, A., De Freitas, M.S., Crepin, M., Figueiredo, C.C., Morandi, V.
格式: Artigo
語言:English
出版: Associação Brasileira de Divulgação Científica 2005
主題:
Alpha2ß1 integrin
Disintegrin
Snake venom
Adhesion
Gene expression
Extracellular matrix
在線閱讀:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2005001000007&lng=en&tlng=en
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