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Sunitinib in the therapy of malignant paragangliomas: report on the efficacy in a SDHB mutation carrier and review of the literature
SUMMARY Metastatic pheochromocytomas (PHEOs) and paragangliomas (sPGLs) are rare neural crest-derived tumors with a poor prognosis. About 50% of them are due to germ-line mutations of the SDHB gene. At present, there is no cure for these tumors. Their therapy is palliative and represented by differe...
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| Publicado no: | Archives of Endocrinology and Metabolism Archives of Endocrinology and Metabolism, Volume: 61, Issue: 1, Pages: 90-97, Published: 10 OCT 2016 |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | English |
| Publicado em: |
Sociedade Brasileira de Endocrinologia e Metabologia
2016
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| Acesso em linha: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S2359-39972017000100090&lng=en&tlng=en |
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