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Antigen-stimulated Activation of Phospholipase D1b by Rac1, ARF6, and PKCα in RBL-2H3 Cells

Phospholipase D (PLD) activity can be detected in response to many agonists in most cell types; however, the pathway from receptor occupation to enzyme activation remains unclear. In vitro PLD1b activity is phosphatidylinositol 4,5-bisphosphate dependent via an N-terminal PH domain and is stimulated...

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Detalhes bibliográficos
Main Authors: Powner, Dale J., Hodgkin, Matthew N., Wakelam, Michael J.O.
Formato: Artigo
Idioma:en
Publicado em: The American Society for Cell Biology 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC102266/
https://ncbi.nlm.nih.gov/pubmed/11950936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.01-05-0235
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