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Mutant Influenza Viruses with a Defective NS1 Protein Cannot Block the Activation of PKR in Infected Cells

A short model genome RNA and also the genome RNA of influenza A virus bearing both 5′- and 3′-terminal common sequences activated the interferon-induced double-stranded-RNA-dependent protein kinase, PKR, by stimulating autophosphorylation in vitro. The activated PKR catalyzed phosphorylation of the...

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Detalhes bibliográficos
Main Authors: Hatada, Eriko, Saito, Sakura, Fukuda, Ryuji
Formato: Artigo
Idioma:en
Publicado em: American Society for Microbiology 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC104489/
https://ncbi.nlm.nih.gov/pubmed/9971827
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