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Estimate of the Frequency of Human Immunodeficiency Virus Type 1 Protease Inhibitor Resistance within Unselected Virus Populations In Vitro

The frequency of drug-resistant human immunodeficiency virus type 1 (HIV-1) variants in virus populations not previously exposed to drug was determined in vitro by using HIV-1(RF) and the protease inhibitor SC-55389A. Two variants with single mutations responsible for drug resistance (V82A and N88S)...

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Detalhes bibliográficos
Main Authors: Tucker, Simon P., Stiebel, Thomas R., Potts, Karen E., Smidt, Mary L., Bryant, Martin L.
Formato: Artigo
Idioma:en
Publicado em: American Society for Microbiology 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC105443/
https://ncbi.nlm.nih.gov/pubmed/9527815
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