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Human Immunodeficiency Virus Type 1 cDNA Integration: New Aromatic Hydroxylated Inhibitors and Studies of the Inhibition Mechanism

Integration of the human immunodeficiency virus type 1 (HIV-1) cDNA is a required step for viral replication. Integrase, the virus-encoded enzyme important for integration, has not yet been exploited as a target for clinically useful inhibitors. Here we report on the identification of new polyhydrox...

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Detalhes bibliográficos
Main Authors: Farnet, C. M., Wang, B., Hansen, M., Lipford, J. R., Zalkow, L., Robinson, W. E., Siegel, J., Bushman, F.
Formato: Artigo
Idioma:en
Publicado em: American Society for Microbiology 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC105796/
https://ncbi.nlm.nih.gov/pubmed/9736543
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