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Haplotype analysis of common variants in the BRCA1 gene and risk of sporadic breast cancer

INTRODUCTION: Truncation mutations in the BRCA1 gene cause a substantial increase in risk of breast cancer. However, these mutations are rare in the general population and account for little of the overall incidence of sporadic breast cancer. METHOD: We used whole-gene resequencing data to select ha...

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Detalhes bibliográficos
Main Authors: Cox, David G, Kraft, Peter, Hankinson, Susan E, Hunter, David J
Formato: Artigo
Idioma:English
Publicado em: BioMed Central 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1064127/
https://ncbi.nlm.nih.gov/pubmed/15743496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr973
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