An Adenovirus Vector with Genetically Modified Fibers Demonstrates Expanded Tropism via Utilization of a Coxsackievirus and Adenovirus Receptor-Independent Cell Entry Mechanism

Recombinant adenoviruses (Ad) have become the vector system of choice for a variety of gene therapy applications. However, the utility of Ad vectors is limited due to the low efficiency of Ad-mediated gene transfer to cells expressing marginal levels of the coxsackievirus and adenovirus receptor (CA...

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Main Authors: Dmitriev, Igor, Krasnykh, Victor, Miller, C. Ryan, Wang, Minghui, Kashentseva, Elena, Mikheeva, Galina, Belousova, Natalya, Curiel, David T., Meng, Xiang-Jin, Halbur, Patrick G., Shapiro, Max S., Govindarajan, Sugantha, Bruna, Jeremy D., Mushahwar, Isa K., Purcell, Robert H., Emerson, Suzanne U., Shrivastava, Anju, Manna, Sunil K., Ray, Ranjit, Aggarwal, Bharat B., Lin, Yi-Ling, Liao, Ching-Len, Chen, Li-Kuang, Yeh, Chia-Tsui, Liu, Chiu-I, Ma, Shiou-Hwa, Huang, Yu-Ying, Huang, Yue-Ling, Kao, Chuan-Liang, King, Chwan-Chuen, Cardinali, Giorgia, Gentile, Massimo, Cirone, Mara, Zompetta, Claudia, Frati, Luigi, Faggioni, Alberto, Torrisi, Maria Rosaria, Takimoto, Toru, Bousse, Tatiana, Coronel, Elizabeth C., Scroggs, Ruth Ann, Portner, Allen, Shoya, Yuko, Kobayashi, Takeshi, Koda, Toshiaki, Ikuta, Kazuyoshi, Kakinuma, Mitsuaki, Kishi, Masahiko, Sakaida, Hitoshi, Hori, Toshiyuki, Yonezawa, Akihito, Sato, Akihiko, Isaka, Yoshitaka, Yoshie, Osamu, Hattori, Toshio, Uchiyama, Takashi, Weisshart, Klaus, Taneja, Poonam, Fanning, Ellen, Medstrand, Patrik, Mager, Dixie L., Frankel, Sarah S., Steinman, Ralph M., Michael, Nelson L., Kim, Silvia Ratto, Bhardwaj, Nina, Pope, Melissa, Louder, Mark K., Ehrenberg, Philip K., Parren, Paul W. H. I., Burton, Dennis R., Katinger, Hermann, VanCott, Thomas C., Robb, Merlin L., Birx, Deborah L., Mascola, John R., Halbert, Christine L., Standaert, Thomas A., Wilson, Christopher B., Miller, A. Dusty, Osterrieder, Nikolaus, Neubauer, Antonie, Brandmüller, Christine, Kaaden, Oskar-Rüger, O’Callaghan, Dennis J., Wang, Guoshun, Davidson, Beverly L., Melchert, Paul, Slepushkin, Vladimir A., van Es, Helmuth H. G., Bodner, Mordechai, Jolly, Doug J., McCray, Paul B., Howe, Anita Y. M., Jung, Jae U., Desrosiers, Ronald C., Mah, Cathryn, Qing, Keyun, Khuntirat, Benjawan, Ponnazhagan, Selvarangan, Wang, Xu-Shan, Kube, Dagmar M., Yoder, Mervin C., Srivastava, Arun, Shen, Shih-Cheng, Shen, Jing-Yih, Su, Hong-Lin, Sun, Yi-Ching, Chen, Ko-Pei, Spenlehauer, Catherine, Saragosti, Sentob, Fleury, Hervé J. A., Kirn, André, Aubertin, Anne-Marie, Moog, Christiane, Xu, Aimin, Bellamy, A. Richard, Taylor, John A., Zufferey, Romain, Dull, Thomas, Mandel, Ronald J., Bukovsky, Anatoly, Quiroz, Dulce, Naldini, Luigi, Trono, Didier, Herrmann, Christine H., Carroll, Richard G., Wei, Ping, Jones, Katherine A., Rice, Andrew P., Otero, Glen C., Hope, Thomas J., Wu, Baodong, White, K. Andrew, Lee, Shing-Yi, Howard, Thomas M., Rasheed, Suraiya, Monaco, Maria Chiara G., Jensen, Peter N., Hou, Jean, Durham, Linda C., Major, Eugene O., Sanderson, Christopher M., Smith, Geoffrey L., Kuhen, Kelli L., Vessey, Jill W., Samuel, Charles E., Sopper, Sieghart, Sauer, Ursula, Hemm, Susanne, Demuth, Monika, Müller, Justus, Stahl-Hennig, Christiane, Hunsmann, Gerhard, ter Meulen, Volker, Dörries, Rüdiger, Harada, Shizuko, Yalamanchili, Ramana, Kieff, Elliott, Lavillette, Dimitri, Maurice, Marielle, Roche, Catherine, Russell, Stephen J., Sitbon, Marc, Cosset, François-Loïc, Nüesch, Jürg P. F., Dettwiler, Sabine, Corbau, Romuald, Rommelaere, Jean, Tolle, Tanja K., Glebe, Dieter, Linder, Monica, Linder, Dietmar, Schmitt, Sigrid, Geyer, Rudolf, Gerlich, Wolfram H., Bettarel, Yvan, Sime-Ngando, Telesphore, Amblard, Christian, Laveran, Henri, Kato, Yasuo, Ooi, Ryoko, Asano, Yasuhisa, Takeuchi, Yasuhiro, Patience, Clive, Magre, Saema, Weiss, Robin A., Banerjee, Papia T., Le Tissier, Paul, Stoye, Jonathan P., De Wever, Helene, Cole, James R., Fettig, Michael R., Hogan, Deborah A., Tiedje, James M., Cocchi, Francesca, Menotti, Laura, Mirandola, Prisco, Lopez, Marc, Campadelli-Fiume, Gabriella, Pham, P. L., Dupont, I., Roy, D., Lapointe, G., Cerning, J., Guarino, Linda A., Jin, Jianping, Dong, Wen, Civolani, Claudio, Barghini, Paolo, Roncetti, Anna Rita, Ruzzi, Maurizio, Schiesser, Alma, Guiliani, Nicolas, Jerez, Carlos A., Gross, Christian H., Shuman, Stewart, Atiles, Myrta W., Dudley, Edward G., Steele, James L., Siegumfeldt, Henrik, Björn Rechinger, K., Jakobsen, Mogens, McChesney, Michael B., Collins, Jennifer R., Lu, Ding, Lu, Xusheng, Torten, Judith, Ashley, Rhoda L., Cloyd, Miles W., Miller, Christopher J., Zhao, Jian-Shen, Singh, Ajay, Huang, Xiao-Dong, Ward, Owen P., Sullivan, Daniel G., Wilson, Jeffrey J., Carithers, Robert L., Perkins, James D., Gretch, David R., Skory, Christopher D., Wyman, Michael, Davies, John T., Crawford, David W., Purdie, Duncan A.
Formato: Artigo
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Publicado em: American Society for Microbiology 1998
Assuntos:
Gene Therapy
Viral Pathogenesis and Immunity
Animal Viruses
Virus-Cell Interactions
Plant Viruses
Viral and Cellular Oncogenes
Methods
Physiology and Biotechnology
Environmental Microbiology and Biodegradation
Food Microbiology
Genetics and Molecular Biology
Microbial Ecology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC110480/
https://ncbi.nlm.nih.gov/pubmed/9811704
https://ncbi.nlm.nih.gov/pmc/articles/PMC110481/
https://ncbi.nlm.nih.gov/pubmed/9811705
https://ncbi.nlm.nih.gov/pmc/articles/PMC110482/
https://ncbi.nlm.nih.gov/pubmed/9811706
https://ncbi.nlm.nih.gov/pmc/articles/PMC110483/
https://ncbi.nlm.nih.gov/pubmed/9811707
https://ncbi.nlm.nih.gov/pmc/articles/PMC110484/
https://ncbi.nlm.nih.gov/pubmed/9811708
https://ncbi.nlm.nih.gov/pmc/articles/PMC110485/
https://ncbi.nlm.nih.gov/pubmed/9811709
https://ncbi.nlm.nih.gov/pmc/articles/PMC110486/
https://ncbi.nlm.nih.gov/pubmed/9811710
https://ncbi.nlm.nih.gov/pmc/articles/PMC110487/
https://ncbi.nlm.nih.gov/pubmed/9811711
https://ncbi.nlm.nih.gov/pmc/articles/PMC110488/
https://ncbi.nlm.nih.gov/pubmed/9811712
https://ncbi.nlm.nih.gov/pmc/articles/PMC110489/
https://ncbi.nlm.nih.gov/pubmed/9811713
https://ncbi.nlm.nih.gov/pmc/articles/PMC110490/
https://ncbi.nlm.nih.gov/pubmed/9811714
https://ncbi.nlm.nih.gov/pmc/articles/PMC110491/
https://ncbi.nlm.nih.gov/pubmed/9811715
https://ncbi.nlm.nih.gov/pmc/articles/PMC110492/
https://ncbi.nlm.nih.gov/pubmed/9811716
https://ncbi.nlm.nih.gov/pmc/articles/PMC110493/
https://ncbi.nlm.nih.gov/pubmed/9811717
https://ncbi.nlm.nih.gov/pmc/articles/PMC110494/
https://ncbi.nlm.nih.gov/pubmed/9811718
https://ncbi.nlm.nih.gov/pmc/articles/PMC110495/
https://ncbi.nlm.nih.gov/pubmed/9811719
https://ncbi.nlm.nih.gov/pmc/articles/PMC110496/
https://ncbi.nlm.nih.gov/pubmed/9811720
https://ncbi.nlm.nih.gov/pmc/articles/PMC110497/
https://ncbi.nlm.nih.gov/pubmed/9811721
https://ncbi.nlm.nih.gov/pmc/articles/PMC110498/
https://ncbi.nlm.nih.gov/pubmed/9811722
https://ncbi.nlm.nih.gov/pmc/articles/PMC110499/
https://ncbi.nlm.nih.gov/pubmed/9811723
https://ncbi.nlm.nih.gov/pmc/articles/PMC110500/
https://ncbi.nlm.nih.gov/pubmed/9811724
https://ncbi.nlm.nih.gov/pmc/articles/PMC110501/
https://ncbi.nlm.nih.gov/pubmed/9811725
https://ncbi.nlm.nih.gov/pmc/articles/PMC110502/
https://ncbi.nlm.nih.gov/pubmed/9811726
https://ncbi.nlm.nih.gov/pmc/articles/PMC110503/
https://ncbi.nlm.nih.gov/pubmed/9811727
https://ncbi.nlm.nih.gov/pmc/articles/PMC110504/
https://ncbi.nlm.nih.gov/pubmed/9811728
https://ncbi.nlm.nih.gov/pmc/articles/PMC110505/
https://ncbi.nlm.nih.gov/pubmed/9811729
https://ncbi.nlm.nih.gov/pmc/articles/PMC110506/
https://ncbi.nlm.nih.gov/pubmed/9811730
https://ncbi.nlm.nih.gov/pmc/articles/PMC110507/
https://ncbi.nlm.nih.gov/pubmed/9811731
https://ncbi.nlm.nih.gov/pmc/articles/PMC110508/
https://ncbi.nlm.nih.gov/pubmed/9811732
https://ncbi.nlm.nih.gov/pmc/articles/PMC110509/
https://ncbi.nlm.nih.gov/pubmed/9811733
https://ncbi.nlm.nih.gov/pmc/articles/PMC110510/
https://ncbi.nlm.nih.gov/pubmed/9811734
https://ncbi.nlm.nih.gov/pmc/articles/PMC110511/
https://ncbi.nlm.nih.gov/pubmed/9811735
https://ncbi.nlm.nih.gov/pmc/articles/PMC110512/
https://ncbi.nlm.nih.gov/pubmed/10831400
https://ncbi.nlm.nih.gov/pmc/articles/PMC110513/
https://ncbi.nlm.nih.gov/pubmed/10831401
https://ncbi.nlm.nih.gov/pmc/articles/PMC110514/
https://ncbi.nlm.nih.gov/pubmed/9811736
https://ncbi.nlm.nih.gov/pmc/articles/PMC110515/
https://ncbi.nlm.nih.gov/pubmed/10831402
https://ncbi.nlm.nih.gov/pmc/articles/PMC110516/
https://ncbi.nlm.nih.gov/pubmed/9811737
https://ncbi.nlm.nih.gov/pmc/articles/PMC110517/
https://ncbi.nlm.nih.gov/pubmed/10831403
https://ncbi.nlm.nih.gov/pmc/articles/PMC110518/
https://ncbi.nlm.nih.gov/pubmed/9811738
https://ncbi.nlm.nih.gov/pmc/articles/PMC110519/
https://ncbi.nlm.nih.gov/pubmed/10831404
https://ncbi.nlm.nih.gov/pmc/articles/PMC110520/
https://ncbi.nlm.nih.gov/pubmed/9811739
https://ncbi.nlm.nih.gov/pmc/articles/PMC110521/
https://ncbi.nlm.nih.gov/pubmed/10831405
https://ncbi.nlm.nih.gov/pmc/articles/PMC110522/
https://ncbi.nlm.nih.gov/pubmed/9811740
https://ncbi.nlm.nih.gov/pmc/articles/PMC110523/
https://ncbi.nlm.nih.gov/pubmed/10831406
https://ncbi.nlm.nih.gov/pmc/articles/PMC110524/
https://ncbi.nlm.nih.gov/pubmed/10831407
https://ncbi.nlm.nih.gov/pmc/articles/PMC110525/
https://ncbi.nlm.nih.gov/pubmed/9811741
https://ncbi.nlm.nih.gov/pmc/articles/PMC110526/
https://ncbi.nlm.nih.gov/pubmed/10831408
https://ncbi.nlm.nih.gov/pmc/articles/PMC110527/
https://ncbi.nlm.nih.gov/pubmed/9811742
https://ncbi.nlm.nih.gov/pmc/articles/PMC110528/
https://ncbi.nlm.nih.gov/pubmed/10831409
https://ncbi.nlm.nih.gov/pmc/articles/PMC110529/
https://ncbi.nlm.nih.gov/pubmed/10831410
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https://ncbi.nlm.nih.gov/pmc/articles/PMC110480/
https://ncbi.nlm.nih.gov/pubmed/9811704
https://ncbi.nlm.nih.gov/pmc/articles/PMC110481/
https://ncbi.nlm.nih.gov/pubmed/9811705
https://ncbi.nlm.nih.gov/pmc/articles/PMC110482/
https://ncbi.nlm.nih.gov/pubmed/9811706
https://ncbi.nlm.nih.gov/pmc/articles/PMC110483/
https://ncbi.nlm.nih.gov/pubmed/9811707
https://ncbi.nlm.nih.gov/pmc/articles/PMC110484/
https://ncbi.nlm.nih.gov/pubmed/9811708
https://ncbi.nlm.nih.gov/pmc/articles/PMC110485/
https://ncbi.nlm.nih.gov/pubmed/9811709
https://ncbi.nlm.nih.gov/pmc/articles/PMC110486/
https://ncbi.nlm.nih.gov/pubmed/9811710
https://ncbi.nlm.nih.gov/pmc/articles/PMC110487/
https://ncbi.nlm.nih.gov/pubmed/9811711
https://ncbi.nlm.nih.gov/pmc/articles/PMC110488/
https://ncbi.nlm.nih.gov/pubmed/9811712
https://ncbi.nlm.nih.gov/pmc/articles/PMC110489/
https://ncbi.nlm.nih.gov/pubmed/9811713
https://ncbi.nlm.nih.gov/pmc/articles/PMC110490/
https://ncbi.nlm.nih.gov/pubmed/9811714
https://ncbi.nlm.nih.gov/pmc/articles/PMC110491/
https://ncbi.nlm.nih.gov/pubmed/9811715
https://ncbi.nlm.nih.gov/pmc/articles/PMC110492/
https://ncbi.nlm.nih.gov/pubmed/9811716
https://ncbi.nlm.nih.gov/pmc/articles/PMC110493/
https://ncbi.nlm.nih.gov/pubmed/9811717
https://ncbi.nlm.nih.gov/pmc/articles/PMC110494/
https://ncbi.nlm.nih.gov/pubmed/9811718
https://ncbi.nlm.nih.gov/pmc/articles/PMC110495/
https://ncbi.nlm.nih.gov/pubmed/9811719
https://ncbi.nlm.nih.gov/pmc/articles/PMC110496/
https://ncbi.nlm.nih.gov/pubmed/9811720
https://ncbi.nlm.nih.gov/pmc/articles/PMC110497/
https://ncbi.nlm.nih.gov/pubmed/9811721
https://ncbi.nlm.nih.gov/pmc/articles/PMC110498/
https://ncbi.nlm.nih.gov/pubmed/9811722
https://ncbi.nlm.nih.gov/pmc/articles/PMC110499/
https://ncbi.nlm.nih.gov/pubmed/9811723
https://ncbi.nlm.nih.gov/pmc/articles/PMC110500/
https://ncbi.nlm.nih.gov/pubmed/9811724
https://ncbi.nlm.nih.gov/pmc/articles/PMC110501/
https://ncbi.nlm.nih.gov/pubmed/9811725
https://ncbi.nlm.nih.gov/pmc/articles/PMC110502/
https://ncbi.nlm.nih.gov/pubmed/9811726
https://ncbi.nlm.nih.gov/pmc/articles/PMC110503/
https://ncbi.nlm.nih.gov/pubmed/9811727
https://ncbi.nlm.nih.gov/pmc/articles/PMC110504/
https://ncbi.nlm.nih.gov/pubmed/9811728
https://ncbi.nlm.nih.gov/pmc/articles/PMC110505/
https://ncbi.nlm.nih.gov/pubmed/9811729
https://ncbi.nlm.nih.gov/pmc/articles/PMC110506/
https://ncbi.nlm.nih.gov/pubmed/9811730
https://ncbi.nlm.nih.gov/pmc/articles/PMC110507/
https://ncbi.nlm.nih.gov/pubmed/9811731
https://ncbi.nlm.nih.gov/pmc/articles/PMC110508/
https://ncbi.nlm.nih.gov/pubmed/9811732
https://ncbi.nlm.nih.gov/pmc/articles/PMC110509/
https://ncbi.nlm.nih.gov/pubmed/9811733
https://ncbi.nlm.nih.gov/pmc/articles/PMC110510/
https://ncbi.nlm.nih.gov/pubmed/9811734
https://ncbi.nlm.nih.gov/pmc/articles/PMC110511/
https://ncbi.nlm.nih.gov/pubmed/9811735
https://ncbi.nlm.nih.gov/pmc/articles/PMC110512/
https://ncbi.nlm.nih.gov/pubmed/10831400
https://ncbi.nlm.nih.gov/pmc/articles/PMC110513/
https://ncbi.nlm.nih.gov/pubmed/10831401
https://ncbi.nlm.nih.gov/pmc/articles/PMC110514/
https://ncbi.nlm.nih.gov/pubmed/9811736
https://ncbi.nlm.nih.gov/pmc/articles/PMC110515/
https://ncbi.nlm.nih.gov/pubmed/10831402
https://ncbi.nlm.nih.gov/pmc/articles/PMC110516/
https://ncbi.nlm.nih.gov/pubmed/9811737
https://ncbi.nlm.nih.gov/pmc/articles/PMC110517/
https://ncbi.nlm.nih.gov/pubmed/10831403
https://ncbi.nlm.nih.gov/pmc/articles/PMC110518/
https://ncbi.nlm.nih.gov/pubmed/9811738
https://ncbi.nlm.nih.gov/pmc/articles/PMC110519/
https://ncbi.nlm.nih.gov/pubmed/10831404
https://ncbi.nlm.nih.gov/pmc/articles/PMC110520/
https://ncbi.nlm.nih.gov/pubmed/9811739
https://ncbi.nlm.nih.gov/pmc/articles/PMC110521/
https://ncbi.nlm.nih.gov/pubmed/10831405
https://ncbi.nlm.nih.gov/pmc/articles/PMC110522/
https://ncbi.nlm.nih.gov/pubmed/9811740
https://ncbi.nlm.nih.gov/pmc/articles/PMC110523/
https://ncbi.nlm.nih.gov/pubmed/10831406
https://ncbi.nlm.nih.gov/pmc/articles/PMC110524/
https://ncbi.nlm.nih.gov/pubmed/10831407
https://ncbi.nlm.nih.gov/pmc/articles/PMC110525/
https://ncbi.nlm.nih.gov/pubmed/9811741
https://ncbi.nlm.nih.gov/pmc/articles/PMC110526/
https://ncbi.nlm.nih.gov/pubmed/10831408
https://ncbi.nlm.nih.gov/pmc/articles/PMC110527/
https://ncbi.nlm.nih.gov/pubmed/9811742
https://ncbi.nlm.nih.gov/pmc/articles/PMC110528/
https://ncbi.nlm.nih.gov/pubmed/10831409
https://ncbi.nlm.nih.gov/pmc/articles/PMC110529/
https://ncbi.nlm.nih.gov/pubmed/10831410

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