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Characterization of subsets of CD4(+) memory T cells reveals early branched pathways of T cell differentiation in humans

The pathways for differentiation of human CD4(+) T cells into functionally distinct subsets of memory cells in vivo are unknown. The identification of these subsets and pathways has clear implications for the design of vaccines and immune-targeted therapies. Here, we show that populations of apparen...

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Detalhes bibliográficos
Main Authors: Song, Kaimei, Rabin, Ronald L., Hill, Brenna J., De Rosa, Stephen C., Perfetto, Stephen P., Zhang, Hongwei H., Foley, John F., Reiner, Jeffrey S., Liu, Jie, Mattapallil, Joseph J., Douek, Daniel C., Roederer, Mario, Farber, Joshua M.
Formato: Artigo
Idioma:English
Publicado em: National Academy of Sciences 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1131816/
https://ncbi.nlm.nih.gov/pubmed/15905333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0409720102
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