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Purified recombinant human prosaposin forms oligomers that bind procathepsin D and affect its autoactivation
Before delivery to endosomes, portions of proCD (procathepsin D) and proSAP (prosaposin) are assembled into complexes. We demonstrate that such complexes are also present in secretions of cultured cells. To study the formation and properties of the complexes, we purified proCD and proSAP from cultur...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , , , , |
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| Μορφή: | Άρθρο |
| Γλώσσα: | English |
| Έκδοση: |
Portland Press Ltd.
2004
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1133744/ https://ncbi.nlm.nih.gov/pubmed/15255780 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20040175 |
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