Substrate-specifying determinants of the nucleotide pyrophosphatases/phosphodiesterases NPP1 and NPP2

The nucleotide pyrophosphatases/phosphodiesterases NPP1 and NPP2/autotaxin are structurally related eukaryotic ecto-enzymes, but display a very different substrate specificity. NPP1 releases nucleoside 5′-monophosphates from various nucleotides, whereas NPP2 mainly functions as a lysophospholipase D...

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Bibliographic Details
Main Authors: Cimpean, Anisoara, Stefan, Cristiana, Gijsbers, Rik, Stalmans, Willy, Bollen, Mathieu
Format: Article
Language:English
Published: Portland Press Ltd. 2004
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1133763/
https://ncbi.nlm.nih.gov/pubmed/15096095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20040465
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https://ncbi.nlm.nih.gov/pmc/articles/PMC1133763/
https://ncbi.nlm.nih.gov/pubmed/15096095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20040465

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