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Hoxa9 transforms primary bone marrow cells through specific collaboration with Meis1a but not Pbx1b.
Hoxa9, Meis1 and Pbx1 encode homeodomaincontaining proteins implicated in leukemic transformation in both mice and humans. Hoxa9, Meis1 and Pbx1 proteins have been shown to physically interact with each other, as Hoxa9 cooperatively binds consensus DNA sequences with Meis1 and with Pbx1, while Meis1...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | English |
| Publicado em: |
1998
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1170707/ https://ncbi.nlm.nih.gov/pubmed/9649441 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/17.13.3714 |
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