Analysis of Rad3 and Chk1 protein kinases defines different checkpoint responses.

Eukaryotic cells respond to DNA damage and S phase replication blocks by arresting cell-cycle progression through the DNA structure checkpoint pathways. In Schizosaccharomyces pombe, the Chk1 kinase is essential for mitotic arrest and is phosphorylated after DNA damage. During S phase, the Cds1 kina...

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Detalhes bibliográficos
Main Authors: Martinho, R G, Lindsay, H D, Flaggs, G, DeMaggio, A J, Hoekstra, M F, Carr, A M, Bentley, N J
Formato: Artigo
Idioma:English
Publicado em: 1998
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1171070/
https://ncbi.nlm.nih.gov/pubmed/9857181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/17.24.7239
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https://ncbi.nlm.nih.gov/pmc/articles/PMC1171070/
https://ncbi.nlm.nih.gov/pubmed/9857181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/17.24.7239

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