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Escherichia coli SeqA protein affects DNA topology and inhibits open complex formation at oriC.
Chromosome replication in Escherichia coli is initiated by the DnaA protein. Binding of DnaA to the origin, oriC, followed by formation of an open complex are the first steps in the initiation process. Based on in vivo studies the SeqA protein has been suggested to function negatively in the initiat...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | English |
| Publicado em: |
1999
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1171560/ https://ncbi.nlm.nih.gov/pubmed/10469666 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/18.17.4882 |
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