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Impaired apoptosis, extended duration of immune responses, and a lupus-like autoimmune disease in IEX-1-transgenic mice
Susceptibility of activated T cells to apoptosis must be tightly regulated to ensure sufficient T cell progeny for an effective response, while allowing a rapid depletion of them at the end of the immune response. We show here that a previously isolated, NF-κB/rel target gene IEX-1 (Immediate Early...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | en |
| Publicado em: |
The National Academy of Sciences
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC117399/ https://ncbi.nlm.nih.gov/pubmed/11782530 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.022326699 |
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