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Integration of Shaker-type K(+) channel, KAT1, into the endoplasmic reticulum membrane: Synergistic insertion of voltage-sensing segments, S3–S4, and independent insertion of pore-forming segments, S5–P–S6

KAT1 is a member of the Shaker family of voltage-dependent K(+) channels, which has six transmembrane segments (called S1–S6), including an amphipathic S4 with several positively charged residues and a hydrophobic pore-forming region (called P) between S5 and S6. In this study, we systematically eva...

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Detalhes bibliográficos
Main Authors: Sato, Yoko, Sakaguchi, Masao, Goshima, Shinobu, Nakamura, Tatsunosuke, Uozumi, Nobuyuki
Formato: Artigo
Idioma:en
Publicado em: The National Academy of Sciences 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC117514/
https://ncbi.nlm.nih.gov/pubmed/11756658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.012399799
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