The Breakpoint Region of the Most Common Isochromosome, i(17q), in Human Neoplasia Is Characterized by a Complex Genomic Architecture with Large, Palindromic, Low-Copy Repeats

Although a great deal of information has accumulated regarding the mechanisms underlying constitutional DNA rearrangements associated with inherited disorders, virtually nothing is known about the molecular processes involved in acquired neoplasia-associated chromosomal rearrangements. Isochromosome...

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Main Authors: Barbouti, Aikaterini, Stankiewicz, Pawel, Nusbaum, Chad, Cuomo, Christina, Cook, April, Höglund, Mattias, Johansson, Bertil, Hagemeijer, Anne, Park, Sung-Sup, Mitelman, Felix, Lupski, James R., Fioretos, Thoas
Formato: Artigo
Idioma:English
Publicado em: The American Society of Human Genetics 2004
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1181896/
https://ncbi.nlm.nih.gov/pubmed/14666446
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https://ncbi.nlm.nih.gov/pmc/articles/PMC1181896/
https://ncbi.nlm.nih.gov/pubmed/14666446

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