Cyclophilin D is a component of mitochondrial permeability transition and mediates neuronal cell death after focal cerebral ischemia

Mitochondrial permeability transition (PT) is a phenomenon induced by high levels of matrix calcium and is characterized by the opening of the PT pore (PTP). Activation of the PTP results in loss of mitochondrial membrane potential, expansion of the matrix, and rupture of the mitochondrial outer mem...

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Detalhes bibliográficos
Main Authors: Schinzel, Anna C., Takeuchi, Osamu, Huang, Zhihong, Fisher, Jill K., Zhou, Zhipeng, Rubens, Jeffery, Hetz, Claudio, Danial, Nika N., Moskowitz, Michael A., Korsmeyer, Stanley J.
Formato: Artigo
Idioma:English
Publicado em: National Academy of Sciences 2005
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1189333/
https://ncbi.nlm.nih.gov/pubmed/16103352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0505294102
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https://ncbi.nlm.nih.gov/pmc/articles/PMC1189333/
https://ncbi.nlm.nih.gov/pubmed/16103352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0505294102

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