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Cytokine regulation of glutamate decarboxylase biosynthesis in isolated rat islets of Langerhans.

Insulin-dependent diabetes mellitus (IDDM) is an autoimmune disease in which cytokines are thought to play an important role in beta-cell destruction and immune regulation. A major target of beta-cell autoimmunity in IDDM is the enzyme glutamate decarboxylase (GAD). We hypothesized that cytokines in...

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Detalhes bibliográficos
Main Authors: Schmidli, R S, Faulkner-Jones, B E, Harrison, L C, James, R F, DeAizpurua, H J
Formato: Artigo
Idioma:English
Publicado em: 1996
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1217544/
https://ncbi.nlm.nih.gov/pubmed/8760354
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