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Molecular mechanism of lysosomal sialidase deficiency in galactosialidosis involves its rapid degradation.

Galactosialidosis is an inherited lysosomal storage disease caused by the combined deficiency of lysosomal sialidase and beta-galactosidase secondary to the deficiency of cathepsin A/protective protein, which is associated with sialidase and beta-galactosidase in a high-molecular weight (1.27MDa) co...

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Detalhes bibliográficos
Main Authors: Vinogradova, M V, Michaud, L, Mezentsev, A V, Lukong, K E, El-Alfy, M, Morales, C R, Potier, M, Pshezhetsky, A V
Formato: Artigo
Idioma:English
Publicado em: 1998
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1219185/
https://ncbi.nlm.nih.gov/pubmed/9480870
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