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Probing protein conformational changes in living cells by using designer binding proteins: Application to the estrogen receptor

A challenge in understanding the mechanism of protein function in biology is to establish the correlation between functional form in the intracellular environment and high-resolution structures obtained with in vitro techniques. Here we present a strategy to probe conformational changes of proteins...

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Detalhes bibliográficos
Main Authors: Koide, Akiko, Abbatiello, Stacy, Rothgery, Lisa, Koide, Shohei
Formato: Artigo
Idioma:en
Publicado em: The National Academy of Sciences 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC122176/
https://ncbi.nlm.nih.gov/pubmed/11818562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.032665299
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