Identification of HTF (HER2 transcription factor) as an AP-2 (activator protein-2) transcription factor and contribution of the HTF binding site to ERBB2 gene overexpression.

The ERBB2 gene is overexpressed in 30% of human breast cancers and this is correlated with poor prognosis. Overexpression of the ERBB2 gene is due to increased transcription and gene amplification. Our previous studies have identified a new cis element in the ERBB2 promoter which is involved in the...

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Detalhes bibliográficos
Main Authors: Vernimmen, Douglas, Begon, Dominique, Salvador, Christophe, Gofflot, Stéphanie, Grooteclaes, Madeleine, Winkler, Rosita
Formato: Artigo
Idioma:English
Publicado em: 2003
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1223148/
https://ncbi.nlm.nih.gov/pubmed/12418962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20021238
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https://ncbi.nlm.nih.gov/pmc/articles/PMC1223148/
https://ncbi.nlm.nih.gov/pubmed/12418962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20021238

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