Failure to increase glucose consumption through the pentose-phosphate pathway results in the death of glucose-6-phosphate dehydrogenase gene-deleted mouse embryonic stem cells subjected to oxidative stress.

Mouse embryonic stem (ES) glucose-6-phosphate (G6P) dehydrogenase-deleted cells ( G6pd delta), obtained by transient Cre recombinase expression in a G6pd -loxed cell line, are unable to produce G6P dehydrogenase (G6PD) protein (EC 1.1.1.42). These G6pd delta cells proliferate in vitro without specia...

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Main Authors: Filosa, Stefania, Fico, Annalisa, Paglialunga, Francesca, Balestrieri, Marco, Crooke, Almudena, Verde, Pasquale, Abrescia, Paolo, Bautista, José M, Martini, Giuseppe
Formato: Artigo
Idioma:English
Publicado em: 2003
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1223222/
https://ncbi.nlm.nih.gov/pubmed/12466018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20021614
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https://ncbi.nlm.nih.gov/pmc/articles/PMC1223222/
https://ncbi.nlm.nih.gov/pubmed/12466018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20021614

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