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Human antibodies against spores of the genus Bacillus: A model study for detection of and protection against anthrax and the bioterrorist threat

A naïve, human single-chain Fv (scFv) phage-display library was used in bio-panning against live, native spores of Bacillus subtilis IFO 3336 suspended in solution. A direct in vitro panning and enzyme-linked immunosorbent assay-based selection afforded a panel of nine scFv-phage clones of which two...

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Detalhes bibliográficos
Main Authors: Zhou, Bin, Wirsching, Peter, Janda, Kim D.
Formato: Artigo
Idioma:en
Publicado em: National Academy of Sciences 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC122754/
https://ncbi.nlm.nih.gov/pubmed/11959974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.082121599
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