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Direct in vivo V(H) to J(H) rearrangement violating the 12/23 rule
V(D)J recombination at the immunoglobulin heavy chain (IgH) locus follows the 12/23 rule to ensure the correct assembly of the variable region gene segments. Here, we report characterization of an in vivo model that allowed us to study recombination violating the 12/23 rule, namely a mouse strain la...
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| Autori principali: | , , , , |
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| Natura: | Articolo |
| Lingua: | English |
| Pubblicazione: |
The Rockefeller University Press
2005
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1237122/ https://ncbi.nlm.nih.gov/pubmed/15699070 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20041577 |
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