Notch signaling is a direct determinant of keratinocyte growth arrest and entry into differentiation

The role of Notch signaling in growth/differentiation control of mammalian epithelial cells is still poorly defined. We show that keratinocyte-specific deletion of the Notch1 gene results in marked epidermal hyperplasia and deregulated expression of multiple differentiation markers. In differentiati...

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Detalhes bibliográficos
Main Authors: Rangarajan, Annapoorni, Talora, Claudio, Okuyama, Ryuhei, Nicolas, Michael, Mammucari, Cristina, Oh, Heysun, Aster, Jon C., Krishna, Sudhir, Metzger, Daniel, Chambon, Pierre, Miele, Lucio, Aguet, Michel, Radtke, Freddy, Dotto, G.Paolo
Formato: Artigo
Idioma:en
Publicado em: Oxford University Press 2001
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC125257/
https://ncbi.nlm.nih.gov/pubmed/11432830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.13.3427
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https://ncbi.nlm.nih.gov/pmc/articles/PMC125257/
https://ncbi.nlm.nih.gov/pubmed/11432830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.13.3427

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