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Handling Marker-Marker Linkage Disequilibrium: Pedigree Analysis with Clustered Markers

Single-nucleotide polymorphisms (SNPs) are rapidly replacing microsatellites as the markers of choice for genetic linkage studies and many other studies of human pedigrees. Here, we describe an efficient approach for modeling linkage disequilibrium (LD) between markers during multipoint analysis of...

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Detalhes bibliográficos
Main Authors: Abecasis, Gonçalo R. , Wigginton, Janis E. 
Formato: Artigo
Idioma:English
Publicado em: American Society of Human Genetics 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1271385/
https://ncbi.nlm.nih.gov/pubmed/16252236
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