Mutations in Cytochrome b Resulting in Atovaquone Resistance Are Associated with Loss of Fitness in Plasmodium falciparum

Drug resistance in malarial parasites has become a major obstacle in the control of the disease. Strategies are urgently needed to control the development of resistance and to possibly reverse existing resistance. One key element required to reverse malaria drug resistance is for the parasites to “p...

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Bibliographic Details
Main Authors: Peters, Jennifer M., Chen, Nanhua, Gatton, Michelle, Korsinczky, Michael, Fowler, Elizabeth V., Manzetti, Sergio, Saul, Allan, Cheng, Qin
Format: Article
Language:en
Published: American Society for Microbiology 2002
Subjects:
Mechanisms of Resistance
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC127342/
https://ncbi.nlm.nih.gov/pubmed/12121915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.46.8.2435-2441.2002
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https://ncbi.nlm.nih.gov/pmc/articles/PMC127342/
https://ncbi.nlm.nih.gov/pubmed/12121915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.46.8.2435-2441.2002

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