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GTP-induced membrane binding and ion channel activity of annexin VI: is annexin VI a GTP biosensor?

Annexin VI (AnxVI) formed ion channels in planar lipid bilayers that were induced by the addition of millimolar guanosine 5'-triphosphate (GTP) at pH 7.4 and that were not accompanied by a penetration of the protein into the membrane hydrophobic region. GTP-influenced interactions of AnxVI with...

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Detalhes bibliográficos
Main Authors: Kirilenko, Aneta, Golczak, Marcin, Pikula, Slawomir, Buchet, Rene, Bandorowicz-Pikula, Joanna
Formato: Artigo
Idioma:English
Publicado em: 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1302061/
https://ncbi.nlm.nih.gov/pubmed/11964259
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