Proapoptotic Triterpene Electrophiles (Avicins) Form Channels in Membranes: Cholesterol Dependence

Avicins, a family of triterpenoid saponins from Acacia victoriae, can regulate the innate stress response in human cells. Their ability to induce apoptosis in transformed cells makes them potential anticancer agents. We report that avicins can form channels in membranes. The conductance reached a st...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Li, Xiao Xian, Davis, Bridgette, Haridas, Valsala, Gutterman, Jordan U., Colombini, Marco
Formato: Artigo
Idioma:English
Publicado em: Biophysical Society 2005
Assuntos:
Channels, Receptors, and Electrical Signaling
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1305354/
https://ncbi.nlm.nih.gov/pubmed/15653745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.104.049403
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Internet

https://ncbi.nlm.nih.gov/pmc/articles/PMC1305354/
https://ncbi.nlm.nih.gov/pubmed/15653745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.104.049403

Registos relacionados