Reduction of Astrogliosis by Early Treatment of Pneumococcal Meningitis Measured by Simultaneous Imaging, In Vivo, of the Pathogen and Host Response

We developed a method for simultaneous in vivo biophotonic monitoring of pneumococcal meningitis and the accompanying neuronal injury in live transgenic mice. Streptococcus pneumoniae engineered for bioluminescence (lux) was used for direct visualization of disease progression and antibiotic treatme...

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Detalhes bibliográficos
Main Authors: Kadurugamuwa, Jagath L., Modi, Kshitij, Coquoz, Olivier, Rice, Brad, Smith, Steven, Contag, Pamela R., Purchio, Tony
Formato: Artigo
Idioma:English
Publicado em: American Society for Microbiology 2005
Assuntos:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1307043/
https://ncbi.nlm.nih.gov/pubmed/16299273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.12.7836-7843.2005
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Internet

https://ncbi.nlm.nih.gov/pmc/articles/PMC1307043/
https://ncbi.nlm.nih.gov/pubmed/16299273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.12.7836-7843.2005

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