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“Genetically-based resistance to the anti-inflammatory effects of methotrexate in the air pouch model of acute inflammation”
OBJECTIVE: Low-dose methotrexate (MTX), a mainstay in the therapy of rheumatoid arthritis, is effective in only 60–70% of patients, a finding mirrored by poor anti-inflammatory efficacy in some animal models, most notably collagen-induced arthritis. To determine whether genetic factors or the model...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | English |
| Publicado em: |
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1343510/ https://ncbi.nlm.nih.gov/pubmed/16059892 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.21208 |
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