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Alternative Splicing Controls the Mechanisms of FAK Autophosphorylation
Focal adhesion kinase (FAK) is activated following integrin engagement or stimulation of transmembrane receptors. Autophosphorylation of FAK on Tyr-397 is a critical event, allowing binding of Src family kinases and activation of signal transduction pathways. Tissue-specific alternative splicing gen...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | en |
| Publicado em: |
American Society for Microbiology
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC134714/ https://ncbi.nlm.nih.gov/pubmed/12391143 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.22.7731-7743.2002 |
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