Function and Evolution of Plasmid-Borne Genes for Pyrimidine Biosynthesis in Borrelia spp.

The thyX gene for thymidylate synthase of the Lyme borreliosis (LB) agent Borrelia burgdorferi is located in a 54-kb linear plasmid. In the present study, we identified an orthologous thymidylate synthase gene in the relapsing fever (RF) agent Borrelia hermsii, located it in a 180-kb linear plasmid,...

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Detalhes bibliográficos
Main Authors: Zhong, Jianmin, Skouloubris, Stephane, Dai, Qiyuan, Myllykallio, Hannu, Barbour, Alan G.
Formato: Artigo
Idioma:English
Publicado em: American Society for Microbiology 2006
Assuntos:
Molecular Biology of Pathogens
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1347342/
https://ncbi.nlm.nih.gov/pubmed/16428394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.188.3.909-918.2006
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https://ncbi.nlm.nih.gov/pmc/articles/PMC1347342/
https://ncbi.nlm.nih.gov/pubmed/16428394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.188.3.909-918.2006

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