Epigenetic regulation of the tumor suppressor gene TCF21 on 6q23-q24 in lung and head and neck cancer

The identification of tumor suppressor genes has classically depended on their localization within recurrent regions of loss of heterozygosity. According to Knudson's two-hit hypothesis, the remaining allele is lost, either genetically or, more recently identified, through epigenetic events. To...

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Detalhes bibliográficos
Main Authors: Smith, Laura T., Lin, Mauting, Brena, Romulo M., Lang, James C., Schuller, David E., Otterson, Gregory A., Morrison, Carl D., Smiraglia, Dominic J., Plass, Christoph
Formato: Artigo
Idioma:English
Publicado em: National Academy of Sciences 2006
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1348006/
https://ncbi.nlm.nih.gov/pubmed/16415157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0510171102
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https://ncbi.nlm.nih.gov/pmc/articles/PMC1348006/
https://ncbi.nlm.nih.gov/pubmed/16415157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0510171102

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