Identification of a Universal Group B Streptococcus Vaccine by Multiple Genome Screen

Group B Streptococcus (GBS) is a multiserotype bacterial pathogen representing a major cause of life-threatening infections in newborns. To develop a broadly protective vaccine, we analyzed the genome sequences of eight GBS isolates and cloned and tested 312 surface proteins as vaccines. Four protei...

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Hlavní autoři: Maione, Domenico, Margarit, Immaculada, Rinaudo, Cira D., Masignani, Vega, Mora, Marirosa, Scarselli, Maria, Tettelin, Hervé, Brettoni, Cecilia, Iacobini, Emilia T., Rosini, Roberto, D’Agostino, Nunzio, Miorin, Lisa, Buccato, Scilla, Mariani, Massimo, Galli, Giuliano, Nogarotto, Renzo, Dei, Vincenzo Nardi, Vegni, Filipo, Fraser, Claire, Mancuso, Giuseppe, Teti, Giuseppe, Madoff, Lawrence C., Paoletti, Lawrence C., Rappuoli, Rino, Kasper, Dennis L., Telford, John L., Grandi, Guido
Médium: Článek
Jazyk:English
Vydáno: 2005
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1351092/
https://ncbi.nlm.nih.gov/pubmed/15994562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1109869
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https://ncbi.nlm.nih.gov/pmc/articles/PMC1351092/
https://ncbi.nlm.nih.gov/pubmed/15994562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1109869

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